Extract SIGMA (EPS) Estimates from a NONMEM Listing File

Parses the SIGMA covariance matrix diagonal (variance of residual errors) and, if available, standard errors and RSE from a NONMEM .lst file.

Usage

fetch_sigmas(lst, digits = NA)

Arguments

lst

An object of class "lst" from read_lst_file().

digits

Integer or NA. Rounding for rse. Default NA.

Value

A tibble with columns:

parameter

Character. Parameter label (e.g. "EPS1").

estimate

Numeric. Diagonal variance estimate.

se

Numeric. Standard error. NA if no covariance step.

rse

Numeric. Relative standard error (%). NA if no covariance step.

Examples

path <- system.file("testdata", "full_cov.lst", package = "lstparsR")
lst  <- read_lst_file(path)
fetch_sigmas(lst)
#> # A tibble: 2 × 4
#>   parameter estimate      se    rse
#>   <chr>        <dbl>   <dbl>  <dbl>
#> 1 EPS1        0.0769 0.00434   5.64
#> 2 EPS2        0.123  0.199   162.